ODCs

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1 OMIM reference -
2 associated genes
20 signs/symptoms

PROTEIN INTERACTIONS: 2

2 OMIM references -
2 associated genes
No signs/symptoms info

Budd-Chiari syndrome

Hypohidrotic ectodermal dysplasia with immunodeficiency

F5	(UniProt - OMIM)		IKBKG	(UniProt - OMIM)
JAK2	(UniProt - OMIM)		NFKBIA	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	JAK2 JAK2	(0.56) (0.52)	IKBKG NFKBIA

Citations in the biomedical literature:

Budd-Chiari syndrome		Hypohidrotic ectodermal dysplasia with immunodeficiency
	Synonym(s): (no synonyms)		Synonym(s): - Anhidrotic ectodermal dysplasia with immunodeficiency - EDA-ID - HED-ID

	Classification (Orphanet): - Rare hepatic disease		Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare genetic disease - Rare immune disease - Rare skin disease

	Classification (ICD10): - Diseases of the circulatory system -		Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -

	Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: variable Average age of death: any age Type of inheritance: multigenic/multifactorial		Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: child / adolescent Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - 1 MeSH reference: D006502		External references: 2 OMIM references - No MeSH references

Budd-Chiari syndrome
	Very frequent - Ascitis - Portal hypertension - Splenomegaly Frequent - Abnormal hepatic enzymes / transaminases - Acute abdominal pain / colic - Cirrhosis - Esophageal varices - Fever / chilling - Hepatocellular liver disease / hepatic failure - Hepatomegaly / liver enlargement (excluding storage disease) Occasional - Acute hepatic failure - Acute ischemic syndrome - Biliary / gallbladder stones / lithiasis / cholecystitis - Gastrointestinal bleeding / hemorrhage / hematemesis / melena / rectorrhagia - Hepatitis / icterus / cholestasis - Intestinal obstruction / ileus - Malabsorption / chronic diarrhea / steatorrhea - Mesenteric / intestinal infarction - Peritonitis / peritoneal abscess - Weight loss / loss of appetite / break in weight curve / general health alteration
Hypohidrotic ectodermal dysplasia with immunodeficiency
(no data available)